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AU72197 : Determination of Tobramycin Using HPAE-IPAD on a Compact IC System: 20 µM tobramycin Be the first to rate this application


Tobramycin is an important aminoglycoside antibiotic used in ophthalmic and intravenous treatments to treat bacterial infections by blocking protein synthesis.[1] Determinations of tobramycin, kanamycin and other aminoglycoside antibiotics have been previously demonstrated by HPAE-IPAD since 2004.[2–6] This document updates Thermo Scientific™ Application Note 61 using a highpressure-capable Dionex Integrion HPIC system equipped with updated EG technology and an electrochemical detector.
Market: BioPharma
Keywords: AAA-Direct waveform, aminoglycoside, aminoglycoside antibiotic, Carbohydrate waveform, CarboPac PA1 column, Eluent Generation, Integrated pulsed amperometric detection (IPAD), Integrated pulsed amperometry, kanamycin, kanamycin B, HPIC, Tobramycin, Kanamycin A, Reagent Free IC, AAA-Direct gold electrode, Integrion HPIC, ED detection, RFIC System, TN21, AU72197, AU 72197
Matrix: 20 µM tobramycin in deionized water
Author: Terri Christison and Jeff Rohrer
Affiliation: Thermo Fisher Scientific, Sunnyvale, CA USA
Uploaded on 11/23/2016.