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AN1148: Assay of Nitrite and Determination of Nitrate Impurity in Sodium Nitrite Using a Reagent-Free Ion Chromatography System
Description
This application note reports our evaluation of the IC method for nitrite assay and nitrate determination in the proposed revision of the United States Pharmacopeia (USP) monograph for sodium nitrite using an electrolytically generated potassium carbonate/bicarbonate eluent to execute the method rather than the manually prepared sodium carbonate/sodium bicarbonate eluent described in the PF proposal.| Market: | BioPharma |
| Keywords: | Drug Substance, Pharmaceutical, USP monograph, suppressed conductivity detection, Dionex IonPac AS12A Column, RFIC System, EPM, K2CO3 eluent |
| Matrix: | Sodium nitrite solution |
| Author: | Jingli Hu; Jeff Rohrer |
| Affiliation: | Thermo Fisher Scientific, Sunnyvale, CA USA |
For Research Use Only. Not for use in diagnostic procedures.
