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AN1148: Assay of Nitrite and Determination of Nitrate Impurity in Sodium Nitrite Using a Reagent-Free Ion Chromatography System

Instrument Type: IC

This application note reports our evaluation of the IC method for nitrite assay and nitrate determination in the proposed revision of the United States Pharmacopeia (USP) monograph for sodium nitrite using an electrolytically generated potassium carbonate/bicarbonate eluent to execute the method rather than the manually prepared sodium carbonate/sodium bicarbonate eluent described in the PF proposal.