AN1002: Determination of Tartaric Acid in Tolterodine Tartrate Drug Products by IC with Suppressed Conductivity Detection
DescriptionThis application demonstrates two faster IC methods that are accurate and reproducible for determination of tartrate in an encapsulated drug product containing the drug substance tolterodine tartrate which used to treat urinary incontinence caused by abnormal bladder contraction. Both methods use an electrolytic suppressor. The one shown here uses an electrolytically-generated potassium hydroxide eluent and IonPac AS20 column that requires only 10 min per analysis.
|Keywords:||Anion-exchange, Anions, Bromide, Chloride, Counter ion, Dionex IonPac AS20 Column, Drug, Drug Product, Fluoride, Ion chromatography, Nitrate, Nitrite, Pharmaceutical, Phosphate, RFIC, Sulfate, Suppressed conductivity, Tartrate, Tolterodine|
|Author:||S. Tukkeeree, C. Chantarasukon, and Jeff Rohrer|
|Affiliation:||Thermo Fisher Scientific|
For Research Use Only. Not for use in diagnostic procedures.