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AN267: Analysis of the Aminoglycoside Antibiotics Kanamycin and Amikacin Matches USP Requirements
Description
The work shown here evaluates the HPAE-PAD assay method described in the USP monographs for kanamycin and amikacin8,9 and describes a revised HPAE-PAD method using a Dionex CarboPac™ MA1 column and disposable Au-on-polytetrafluoroethylene (PTFE) working electrodes for the analysis of kanamycin and amikacin. The described method provides good sensitivity, high sample throughput, and retention time reproducibility for kanamycin and amikacin.| Market: | Pharma |
| Keywords: | amikacin, aminoglycoside, aminoglycoside antibiotic, Antibiotic, CarboPac MA1, Electrochemical detection, kanamycin, kanamycin B, kanamycin sulfate, Monograph, Pharmaceutical, USP, USP monograph, PAD, HPAE-PAD, TN 20, TN 70671, TN20, TN70671, AN 267 |
| Matrix: | Drug |
| Author: | Lipika Basumallick and Jeffrey Rohrer |
| Affiliation: | Thermo Fisher Scientific, Sunnyvale, CA USA |
For Research Use Only. Not for use in diagnostic procedures.
