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High-precision, automated peptide mapping of proteins Be the first to rate this application

automated peptide mapping


The biopharmaceutical industry continues to develop protein-based biotherapeutics in increasing numbers. Due to their complexity and biotechnological production, there are many attributes that need to be analyzed to guarantee their safety and efficacy. Peptide mapping is used to measure several critical quality attributes (CQA) required for the characterization of any biotherapeutic protein. The analysis is used to confirm that the correct sequence has been expressed for the protein and to check for post-translational and chemical modifications.
Market: BioPharma
Keywords: Hypersil GOLD, Peptide mapping, Cytochrome C, Biopharmaceutical, Rituximab, Infliximab, NIBRT, Carbonic anhydrase, Critical quality attribute, KingFisher, Magnetic SMART Digest, Q Exactive Plus MS, QA/QC, Recombinant somatotropin, Vanquish Horizon UHPLC
Matrix: Digest
Author: Amy Farrell, Jonathan Bones, Ken Cook, Suraj Patel, Alexander Schwahn, Jon Bardsley
Affiliation: NIBRT, Dublin, Ireland and Thermo Fisher Scientific, Reinach, Switzerland; Runcorn, UK; Hemel Hempstead, UK
Uploaded on 6/2/2017.

For Research Use Only. Not for use in diagnostic procedures.