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Separation of oxidized and deamidated impurities of Bevacizumab using Hydrophobic Interaction Chromatography (HIC). Be the first to rate this application

Description

The Thermo Scientific Dionex UltiMate 3000 LC Bio-LC system is applied for the Hydrophobic Interaction (HIC) analysis of Bevacizumab. The separation was performed on a Thermo Scientific MabPac HIC-20 column at UV detection of 214 nm. With a total run time of 40 minutes the method allows separation of all oxidized and deamidated impurities of Bevacizumab.
Market: BioPharma
Keywords: HPLC, Bevacizumab, PDA detection, Oxidation, Deamidation, MabPac HIC-20
Matrix: N/A
Author: Manish Singh
Affiliation: Thermo Fisher Scientific, APAC CoE Lab, Ahmedabad, India
Uploaded on 12/9/2016.

For Research Use Only. Not for use in diagnostic procedures.