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Displaying 1-3 of 3 results for Tag: Oxidation

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Separation of oxidized and deamidated impurities of Bevacizumab using Hydrophobic Interaction Chromatography (HIC).

Instrument Type: HPLC (Biocompatible)

The Thermo Scientific Dionex UltiMate 3000 LC Bio-LC system is applied for the Hydrophobic Interaction (HIC) analysis of Bevacizumab. The separation was performed on a Thermo Scientific MabPac HIC-20 column at UV detection of 214 nm. With a total run time of 40 minutes the method allows separation of all oxidized and deamidated impurities of Bevacizumab.

Separation of Oxidized and Deamidated Impurities from Rituximab by using Hydrophobic Interaction Chromatography (HIC)

Instrument Type: HPLC (Biocompatible)

The Thermo Scientific Dionex UltiMate 3000 LC Bio-LC system is applied for the Hydrophobic Interaction (HIC) analysis of Rituximab. The separation was performed on a Thermo Scientific MabPac HIC-20 column at UV detection of 214 nm. With a total run time of 38 minutes the method allows separation of all oxidized and deamidated impurities of Rituximab.

Separation of Oxidized and Deamidated impurities from Rituximab by reverse phase chromatography

Instrument Type: HPLC (Biocompatible)

The Thermo Scientific Dionex UltiMate 3000 Bio-LC system is applied for the reverse phase analysis of Rituximab (Drug Substance sample). The separation was performed on a Thermo Scientific MAbPac RP column. with UV detection at 214 nm. With a total run time of 70 minutes the method allows separation of all oxidized and deamidated impurities of Rituximab