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Separation of Oxidized and Deamidated impurities from Rituximab by reverse phase chromatography
Description
The Thermo Scientific Dionex UltiMate 3000 Bio-LC system is applied for the reverse phase analysis of Rituximab (Drug Substance sample). The separation was performed on a Thermo Scientific MAbPac RP column. with UV detection at 214 nm. With a total run time of 70 minutes the method allows separation of all oxidized and deamidated impurities of Rituximab| Market: | BioPharma |
| Keywords: | HPLC, MAbPac RP, Rituximab, Oxidation, Deamidation |
| Matrix: | N/A |
| Author: | Manish Singh |
| Affiliation: | Thermo Fisher Scientific, APAC CoE Lab, Ahmedabad, India |
For Research Use Only. Not for use in diagnostic procedures.
