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Displaying 1-5 of 8 results for Tag: PDA detection
Separation of oxidized and deamidated impurities of Bevacizumab using Hydrophobic Interaction Chromatography (HIC).
Instrument Type: HPLC (Biocompatible)The Thermo Scientific Dionex UltiMate 3000 LC Bio-LC system is applied for the Hydrophobic Interaction (HIC) analysis of Bevacizumab. The separation was performed on a Thermo Scientific MabPac HIC-20 column at UV detection of 214 nm. With a total run time of 40 minutes the method allows separation of all oxidized and deamidated impurities of Bevacizumab.
Separation of Oxidized and Deamidated Impurities from Rituximab by using Hydrophobic Interaction Chromatography (HIC)
Instrument Type: HPLC (Biocompatible)The Thermo Scientific Dionex UltiMate 3000 LC Bio-LC system is applied for the Hydrophobic Interaction (HIC) analysis of Rituximab. The separation was performed on a Thermo Scientific MabPac HIC-20 column at UV detection of 214 nm. With a total run time of 38 minutes the method allows separation of all oxidized and deamidated impurities of Rituximab.
Separation of Acidic and Basic charge variants of Denosumab by Ion Exchange chromatography using pH Gradient Buffers
Instrument Type: HPLC (Biocompatible)The Thermo Scientific Dionex UltiMate 3000 LC Bio-LC system is applied for the Ion Exchange analysis of Denosumab. The separation was performed on a Thermo Scientific MAbPac SCX-10 and pH gradient buffers with a UV detection at 280 nm. With a run time of 50 minutes the method allows easy separation of charge variants of Denosumab.
Separation of Acidic and Basic charge variants of Denosumab by Ion Exchange chromatography using Salt Gradient Method
Instrument Type: HPLC (Biocompatible)The Thermo Scientific Dionex UltiMate 3000 LC Bio-LC system is applied for the Ion Exchange analysis of Denosumab. The separation was performed on a Thermo Scientific MabPac SCX-10 column with a UV detection at 220 nm. With a run time of 65 minutes the method allows easy separation of charge variants of Denosumab.
Separation of Aggregates, Dimer and Fragments from Rituximab by using Size Exclusion Chromatography.
Instrument Type: HPLC (Biocompatible)The Thermo Scientific Dionex UltiMate 3000 LC Bio-LC system is applied for the Size exclusion analysis of Rituximab. The separation was performed on a Thermo Scientific MabPac SEC-1 column with a UV detection at 220 nm. With a run time of 30 minutes, the method allows easy separation of Aggregates and Dimer of Rituximab
