Thermo Scientific AppsLab Library: Separation of Aggregates, Dimer and Fragments from Rituximab by using Size Exclusion Chromatography.

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Separation of Aggregates, Dimer and Fragments from Rituximab by using Size Exclusion Chromatography. Be the first to rate this application

#	Compound Name	Compound Class	RT (min)
1	Aggregate	Impurity	10.68
2	Dimer	Impurity	11.49
3	Rituximab	IgG1	12.78

Description

The Thermo Scientific Dionex UltiMate 3000 LC Bio-LC system is applied for the Size exclusion analysis of Rituximab. The separation was performed on a Thermo Scientific MabPac SEC-1 column with a UV detection at 220 nm. With a run time of 30 minutes, the method allows easy separation of Aggregates and Dimer of Rituximab

Market:	BioPharma
Keywords:	HPLC, Dimer, MAbPac SEC-1, PDA detection, Rituximab, Aggregate
Matrix:	N/A
Author:	Manish Singh
Affiliation:	Thermo Fisher Scientific, APAC CoE Lab, Ahmedabad, India

Uploaded on 9/27/2016.

For Research Use Only. Not for use in diagnostic procedures.

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Separation of Aggregates, Dimer and Fragments from Rituximab by using Size Exclusion Chromatography. Be the first to rate this application

Description

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