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Update of AN151: Determination of 100 ppt Perchlorate MRL Using a Compact Ion Chromatography System Coupled to a Mass Spectrometer
Description
Perchlorate, an industrial contaminant from rockets, munitions, and fireworks, causes thyroid dysfunction in humans, especially pregnant women and children. In 2002, the EPA recommended a Provisional Reference Dose for perchlorate of 1 µg/L in drinking water. In 2015, California established a MCL of 6 µg/L with a Public Health Goal of 1 µg/L. IC-MS can provide lower detection limits (~ 30 ng/L) than conductivity in high-ionic-strength matrices using the MS selectivity at 99/101 m/z. Here we update AN151 with the Integrion IC system combined with the MSQ Plus mass spectrometer.| Market: | Environmental |
| Keywords: | MSQ Plus, Perchlorate, IonPac AS20 column, IC-MS, Integrion, Integrion HPIC, Integrion RFIC, LSSM, IC-ESI, IC-MS perchlorate, laboratory synthetic sample matrix, 99 m/z, 101 m/z, 107 m/z, high ionic matrix, para chlorobenzenesulfonic acid, parachlorobenzenesulfonic acid, parachlorobenzenesulfonic acid (pCBSA), 191 m/z |
| Matrix: | Water |
| Author: | Yukiko Kawahara, Terri Christison |
| Affiliation: | Thermo Fisher Scientific |
For Research Use Only. Not for use in diagnostic procedures.
