We present an IC-MS/MS based method for high-throughput screening and quantitation of polar pesticide residues and their metabolites in water matrices below the current legislative requirements. Direct injection eliminates long and laborious sample preparation and makes the method more sensitive and faster than traditionally used LC-MS/MS methods, which utilize FMOC derivatization. This method can increase cost savings, provide more reliable results, and increase sample throughput.

To demonstrate that oxyhalides and bromide can be successfully determined at concentrations required for regulatory standards and guidelines using a Thermo Scientific™ Dionex™ ion chromatography system equipped with a Thermo Scientific™ Dionex™ IonPac™ AS23-4μm column,Thermo Scientific™ Dionex™ CRD 300 Carbonate Removal Device, and a Thermo Scientific™ Dionex™ AERS™ 500 Carbonate Anion Electrolytically Regenerated Suppressor.

The current work updates the system used for the carbohydrate analysis in AN1089. The new system combines flexibility and ease-of-use with high sensitivity and selectivity, bringing a higher level of convenience and cost effectiveness to simple sugar analysis. The method proposed here separates eight common carbohydrate sugars in less than eight minutes. The shorter run time results in better process economics. Using this method, carbohydrates present in 10 individual biofuel samples were quantified.

We present the reliable and accurate quantitative analysis of contaminants at the pg/mL level in drinking water using the Thermo Scientific EQuan MAX Plus LC-MS system coupled to the Thermo Scientific TSQ Endura triple quadrupole mass spectrometer. Excellent reproducibility was shown for the target compounds in tap water using 1 mL injections at 0.37× maximum effluent concentration.

We present a a liquid chromatography – high-resolution, accurate mass (LC-HRAM) methodology using Orbitrap technology as a sensitive, accurate, and reliable alternative to the use of triple quadrupole mass spectrometers in the quantification of hormones in drinking water according to EPA guidelines. By using different scanning modes within the Q Exactive MS, quantitation on precursor ions and identification of fragments ions are possible. These scanning modes can possibly be used for compliance monitoring in place of a triple quadrupole MS.