AU167: Determination of Tobramycin in Crude and In-Process Production Samples During Manufacturing Using HPAE-IPAD
DescriptionThis update describes how tobramycin and its typical impurities can be determined in manufacturing process matrices using the same HPAE-IPAD method described in AN 61. The same method is used to assay tobramycin that is intentionally degraded, demonstrating its suitability as a stability indicating method. An ICS-6000 can be used for this application.
|Antibiotics, CarboPac PA1 column, HPAE-IPAD, IPAD, kanamycin B, nebramine, Dionex ICS-5000+ ion chromatography system, Fermentation broths, Tobramycin, Kanamycin A, Neamine (neomycin A), ICS-6000
|Valoran Hanko and Jeff Rohrer
|Thermo Fisher Scientific
For Research Use Only. Not for use in diagnostic procedures.