![](/Content/Images/icons/rate.png?v=2511129)
![](/Content/Images/icons/ask_expert.png?v=2511129)
![](/Content/Images/icons/request.png?v=2511129)
![](/Content/Images/icons/favorites.png?v=2511129)
![](/Content/Images/icons/create_parts_list.png?v=2511129)
Parts List
![](/Content/Images/icons/send_email.png)
Friend
![](/Content/Images/icons/print.png?v=2511129)
Find methods for your needs
![](/Content/Images/icons/search_help.png?v=2511129)
AU167: Determination of Tobramycin in Crude and In-Process Production Samples During Manufacturing Using HPAE-IPAD
![determination tobramycin](/Image/AppImage/2204/20180205123038/determination-tobramycin?imageNameOnDisk=2204.png)
Description
This update describes how tobramycin and its typical impurities can be determined in manufacturing process matrices using the same HPAE-IPAD method described in AN 61. The same method is used to assay tobramycin that is intentionally degraded, demonstrating its suitability as a stability indicating method. An ICS-6000 can be used for this application.Market: | BioPharma |
Keywords: | Antibiotics, CarboPac PA1 column, HPAE-IPAD, IPAD, kanamycin B, nebramine, Dionex ICS-5000+ ion chromatography system, Fermentation broths, Tobramycin, Kanamycin A, Neamine (neomycin A), ICS-6000 |
Matrix: | Fermentation broths |
Author: | Valoran Hanko and Jeff Rohrer |
Affiliation: | Thermo Fisher Scientific |
For Research Use Only. Not for use in diagnostic procedures.