AU167: Determination of Tobramycin in Crude and In-Process Production Samples During Manufacturing Using HPAE-IPAD

Instrument Type: IC

This update describes how tobramycin and its typical impurities can be determined in manufacturing process matrices using the same HPAE-IPAD method described in AN 61. The same method is used to assay tobramycin that is intentionally degraded, demonstrating its suitability as a stability indicating method. An ICS-6000 can be used for this application.