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AN298: Determination of Dimethylamine in Metformin HCl Drug Product Using IC with Suppressed Conductivity Detection Be the first to rate this application

an298 determination dimethylamine metformin hcl drug product using ic with suppressed conductivity detection


Metformin (N,N-dimethylimidodicarbonimidic diamide) is a widely prescribed orally administered antidiabetic drug for the treatment of type 2 diabetes. This application presents a IC method used for quantitation of dimethylamine in metformin hydrochloride. This method uses a Thermo Scientific Dionex IonPac CS19 cation-exchange analytical column with methanesulfonic acid eluent produced by an eluent generator. The method separates dimethylamine from other cations typically present in drug products.
Market: Pharma
Keywords: dimethylamine, Dionex IonPac CS19 Column, drug product, Impurities, Metformin, Pharmaceuticals, Reagent-Free Ion Chromatography (RFIC), Amine
Matrix: Tablet
Uploaded on 2/2/2015.

For Research Use Only. Not for use in diagnostic procedures.