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High Resolution LC-MS for Screening and Quantitative Analysis of Antibiotics in Drinking Water Using an Orbitrap and Online Sample Preparation

Description
Most current methodologies for the quantitation of antibiotics in drinking water revolve around analysis using triple stage quadrupole platforms with offline sample preparation. This is a proven technique for the analysis of many contaminants in various types of water samples, but the offline sample preparation steps are time-consuming and prone to operator error and reproducibility problems. We demonstrate the ability to directly inject the water sample without any offline preconcentration. We utilize LC-MS with a Thermo Scientific Exactive Plus Orbitrap MS using HR/AM.Market: | Food and Beverage |
Keywords: | Water analysis, Accela UHPLC, Exactive Plus Orbitrap MS, Online sample prep, High Resolution Accurate Mass (HR/AM) |
Matrix: | Water |
Author: | Jonathan Beck, Charles Yang, Dipankar Ghosh, and Kristi Akervik |
Affiliation: | Thermo Fisher Scientific |
For Research Use Only. Not for use in diagnostic procedures.