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AN1002: Determination of Tartaric Acid in Tolterodine Tartrate Drug Products by IC with Suppressed Conductivity Detection (Carbonate/Bicarbonate Eluent) Be the first to rate this application

an1002 determination tartaric acid tolterodine tartrate drug products by ic with suppressed conductivity detection carbonatebicarbonate eluent


This application demonstrates two faster IC methods that are accurate and reproducible for determination of tartrate in an encapsulated drug product containing the drug substance tolterodine tartrate which used to treat urinary incontinence caused by abnormal bladder contraction. Both methods use an electrolytic suppressor. The method shown here uses an IonPac AS22 column with carbonate/bicarbonate eluent and has an analysis time of 12 min.
Market: Pharma
Keywords: Anion-exchange, Anions, Bromide, Carbonate/bicarbonate, Chloride, Counter ion, Drug, Fluoride, Ion chromatography, IonPac AS22, Nitrate, Nitrite, Pharmaceutical, Phosphate, Sulfate, Suppressed conductivity, Tartrate, Tolterodine
Matrix: Drug
Author: S. Tukkeeree, C. Chantarasukon, and Jeff Rohrer
Affiliation: Thermo Fisher Scientific
Uploaded on 10/28/2015.

For Research Use Only. Not for use in diagnostic procedures.