AN1002: Determination of Tartaric Acid in Tolterodine Tartrate Drug Products by IC with Suppressed Conductivity Detection (Carbonate/Bicarbonate Eluent)
DescriptionThis application demonstrates two faster IC methods that are accurate and reproducible for determination of tartrate in an encapsulated drug product containing the drug substance tolterodine tartrate which used to treat urinary incontinence caused by abnormal bladder contraction. Both methods use an electrolytic suppressor. The method shown here uses an IonPac AS22 column with carbonate/bicarbonate eluent and has an analysis time of 12 min.
|Keywords:||Anion-exchange, Anions, Bromide, Carbonate/bicarbonate, Chloride, Counter ion, Drug, Fluoride, Ion chromatography, IonPac AS22, Nitrate, Nitrite, Pharmaceutical, Phosphate, Sulfate, Suppressed conductivity, Tartrate, Tolterodine|
|Author:||S. Tukkeeree, C. Chantarasukon, and Jeff Rohrer|
|Affiliation:||Thermo Fisher Scientific|
For Research Use Only. Not for use in diagnostic procedures.