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AN1002: Determination of Tartaric Acid in Tolterodine Tartrate Drug Products by IC with Suppressed Conductivity Detection (Carbonate/Bicarbonate Eluent)

Instrument Type: IC

This application demonstrates two faster IC methods that are accurate and reproducible for determination of tartrate in an encapsulated drug product containing the drug substance tolterodine tartrate which used to treat urinary incontinence caused by abnormal bladder contraction. Both methods use an electrolytic suppressor. The method shown here uses an IonPac AS22 column with carbonate/bicarbonate eluent and has an analysis time of 12 min.