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AN1075: Ion Chromatography Assay for Chloride and Sulfate in Adenosine Be the first to rate this application

chloride sulfate adenosine


Adenosine is produced by the condensation of ribose and adenine biochemically or by fermentation. Anions such as chloride and sulfate are possible impurities in adenosine preparations and the U.S. Pharmacopeia (USP) adenosine monograph describes turbidity-based assays to determine the amount of chloride and sulfate in adenosine which are subjective, use toxic chemicals, and generate hazardous waste. This application is a fast ion chromatography (IC)-based method that can meet the assay requirements and replace the USP adenosine monograph’s existing turbidity-based assays.
Market: Pharma
Keywords: Pharmaceutical, Adenosine, Drug Products, Impurities, Reagent-Free Ion Chromatography, Dionex IonPac AS18-4 μm, Fast Separation, RFIC, Chloride, Sulfate, Suppressed Conductivity, AN 1075, AN 70854, AN70854
Matrix: Drug
Author: Lipika Basumallick and Jeffrey Rohrer
Affiliation: Thermo Fisher Scientific, Sunnyvale, CA USA
Uploaded on 3/17/2015.

For Research Use Only. Not for use in diagnostic procedures.