AN1057: Determination of Methylamine in Drug Products
DescriptionMethylamine or monomethylamine (MMA) is widely used in different stages of the preparation of various drug substances and may be retained in the drug substance as process-related or degradation impurities. The work shown here uses a RFIC system with suppressed conductivity detection to determine MMA in drug products. This method uses a Thermo Scientific™ Dionex™ IonPac™ CS19 analytical column with methanesulfonic acid (MSA) eluent produced by an eluent generator. The method separates MMA from other cations typically present in drug products.
|Keywords:||Dionex IonPac CS19 Column, Impurities, Methylamine, MMA, Monomethylamine, Pharmaceutical, Reagent-Free Ion Chromatography, RFIC|
For Research Use Only. Not for use in diagnostic procedures.