We present an IC-MS/MS based method for high-throughput screening and quantitation of polar pesticide residues and their metabolites in water matrices below the current legislative requirements. Direct injection eliminates long and laborious sample preparation and makes the method more sensitive and faster than traditionally used LC-MS/MS methods, which utilize FMOC derivatization. This method can increase cost savings, provide more reliable results, and increase sample throughput.

We present a reliable and cost-effective IC-MS/MS multi-residue method for high-throughput screening and quantitation of polar pesticide residues and their metabolites in food matrices below the current legislative requirements. In contrast to methods described in the literature, sample preparation is simplified and the use of ion chromatography speeds up the separation.

We present a sensitive, robust, fast method to determine and quantify residues of polar pesticides in food samples in complex matrices at required regulatory levels. The Thermo Scientific UltiMate 3400 RSLC system is used in combination with a Thermo Scientific TSQ Quantiva triple quadrupole mass spectrometer to analyze QuPPe method extracts. The robustness of the system allows uninterrupted analysis of up to 500 honey samples and easy cleaning of the ion introduction system.

In this work, the retention of highly polar compounds glyphosate and AMPA was demonstrated using the Thermo Scientific Hypercarb HPLC column using a fast and sensitive method with MS detection. Through its primary retention mechanisms (dispersive and dipole induced interactions) hypercarb shows greater retention and resolution of underivatized glyphosate and AMPA than silica based C18 without requiring an ion pair reagent in the mobile phase.

毛细管离子色谱法同时测定饮用水中痕量碘离子、硫氰酸根和草甘膦，方法简便、稳定，线性范围内相关性好，准确度高，受其他因素干扰小。还具有样品用量少，淋洗液消耗极低等优点，可以用于水中痕量碘离子、硫氰酸根和草甘膦的同时测定，具有较高的实用价值。