In the electronics industry, ionic contamination in the range of parts per trillion (ppt, ng/L) to parts per billion (ppb) concentrations is a major concern, causing corrosion-related failures in production and final product. Ionic contamination is increasingly important as the devices decrease to size. This technical note demonstrates automated calibration and water purification on an ICS-5000+ HPIC dual IC system to minimize the system and environmental contamination which resulted in increased sensitivity to double-digit-ppt concentrations. An ICS-6000 can be used for this application.

In the electronics industry, ionic contamination, in the range of parts per trillion (ppt, ng/L) to parts per billion (ppb) concentrations, is a major concern causing corrosion-related failures in production and as a product. Ionic contamination is increasingly important as the devices decrease to size. This technical note demonstrates automated calibration and water purification on an ICS-5000+ HPIC dual IC system to minimize the system and environmental contamination which resulted in increased sensitivity to double-digit-ppt concentrations. An ICS-6000 can be used for this application.

本文研究的三种甜味剂（甜蜜素、安赛蜜、糖精钠）和两种防腐剂（山 梨酸钾、苯甲酸钠），均有国标测定方法，但测定条件不同，不能实现同时 检测。其中，甜蜜素国标测定方法为气相色谱法[4]，但其前处理方法比较复 杂，干扰因素多[5]。甜蜜素的分析也可采用高效液相色谱法，紫外检测，但信 号较弱，灵敏度低[6]。通常需采用柱前衍生的方法以增强紫外信号的强度，但 同时增加了样品前处理步骤，且不能同时测定其它甜味剂。 这五种物质分子中都带有易电离的阴离子基团，因此可通过阴离子交换 分离，电导检测器检测[7]，因此离子色谱作为合适的测定方法得到很快发展。 本方法采用IonPac AS17-C阴离子交换色谱柱，通过淋洗条件优化，使用两 阶等浓度氢氧化钾淋洗液洗脱，使待测离子和样品基体获得了良好的分离效 果，在多种食品测定中获得了成功的应用。

Determinations of trace anions in ultrapure water are important to the electronics industry. In this record, determinations of ng/L (ppt) anions using large volume concentration are made possible by the Electrolytic Water Purifier(EWP) and AutoPrep modules. Calibration standards are prepared using the AutoPrep large and small loops and EWP-purified water diluent, thereby increasing sensitivity by eliminating sources of contamination. The trace anions are separated on an IonPac AS17-C column designed to improve low level sulfate determinations using a Dionex Integrion compact IC system.

Determinations of trace anions in ultrapure water are important to the electronics industry. In this record, determinations of ng/L (ppt) anions using large volume concentration are made possible by the Electrolytic Water Purifier(EWP) and AutoPrep modules. Calibration standards are prepared using the AutoPrep large and small loops and EWP-purified water diluent, thereby increasing sensitivity by eliminating sources of contamination. The trace anions are separated on an IonPac AS17-C column designed to improve low level sulfate determinations using a Dionex Integrion compact IC system.