The Thermo Scientific Dionex UltiMate 3000 LC system is applied for the assay and related substances analysis of minocycline hydrochloride. The analysis was performed on a Thermo Scientific Hypersil GOLD C8 HPLC column using the method described in the EP 8.0. The results obtained for resolution and theoretical plates met the criteria stated in the EP. The results obtained for resolution between the peaks due to impurity A and minocycline was 4.3 (EP criteria of minimum 2.0) and theoretical plates for minocycline (0.125 mg/mL) was 6376 (EP criteria of minimum 3000).

The Thermo Scientific Dionex UltiMate 3000 LC system is applied for the analysis of amlodipine and perindopril in solid dosage formulation. The separation was performed on a Thermo Scientific Hypersil GOLD C8 HPLC column using a reversed-phase method with UV detection at 210 nm.

The Thermo Scientific HPLC system is applied for the analysis of linoleic acid. The separation is performed on a Thermo Scientific Hypersil GOLD C8 HPLC column, with UV detection at 200 nm.

The Thermo Scientific HPLC system is applied for the analysis of triazines. The separation is performed on a Thermo Scientific Hypersil GOLD C8 HPLC column, with UV detection at 220 nm.

The Thermo Scientific HPLC system is applied for the analysis of contaminants in soil. The separation is performed on a Thermo Scientific Hypersil GOLD C8 HPLC column, with UV detection at 220 nm.