Forensic toxicologists need an economical solution to screen for a virtually unlimited number of compounds in urine. Here we present a method for screening using a dilute-and-shoot approach with the Q Exactive Focus mass spectrometer and Thermo Scientific ToxFinder software. For forensic use only.

In this application note, triclosan-contaminated samples of tap water were simulated by adding known amounts of triclosan-containing liquid hand soap to Sunnyvale tap water. The Dionex AutoTrace 280 instrument along with the high-surface-area, hydrophilic, reversed-phase cartridges were used to concentrate triclosan. The contents of the cartridge eluent were then separated on a reversed phase column using HPLC with UV detection.

Pharmaceuticals and personal care products (PPCPs) and endocrine disrupting chemicals (EDCs) detected in surface and drinking waters, as well as in treated wastewater. They are an issue of increasing international attention due to potential environmental impacts. We developed an analytical method capable of determining PPCPs and their by-products in wastewater treatment plant (WWTP) samples. This workflow was applied in a survey of 35 permeate samples obtained from a pilot anaerobic membrane bioreactor (AnMBR).

There is growing environmental concern regarding the health impact of trace levels of pharmaceuticals and personal care products (PPCPs) in water resources. In response, the U.S. Environmental Protection Agency (EPA) published Method 1694, which determines dozens of PPCPs in water, soil, sediment, and biosolids by HPLC-MS/MS. We demonstrate a progressive approach to analyzing PPCPs in environmental sources of water at the ng/L level with online sample preparation using small volumes of water, thus saving time and reducing the cost of analysis.

The Thermo Scientific HPLC system is applied for the analysis of miconazole in athlete's foot ointment. The separation is performed on a Thermo Scientific Acclaim 120 C18 column, with UV detection at 225 nm.