Fast and Easy separation of 23 drugs of abuse, including the adequate and stable resolution of isobaric opioids from human urine. The new Thermo Scientific™ Accucore™ Biphenyl solid core column is used in combination with the Thermo Scientific™ Horizon™ UHPLC system and Thermo Scientific™ TSQ Quantiva™ MS/MS system.
Forensic toxicologists need an economical solution to screen for a virtually unlimited number of compounds in urine. Here we present a method for screening using a dilute-and-shoot approach with the Q Exactive Focus mass spectrometer and Thermo Scientific ToxFinder software. For forensic use only.
Forensic toxicologists face an ever-expanding list of compounds for analysis. This note presents work done using a next-generation triple quadrupole mass spectrometer with fast SRM acquisition speed for quantitation of 122 analytes in a single chromatographic run, where scan speed does not impact sensitivity or quantitative performance. Compounds analyzed include opiates, opioids, benzodiazepines, barbiturates, amphetamines, tricyclic antidepressants, illicit compounds, and more. For forensic use only.
The analysis of food and environmental samples for contaminants by LC-MS has become a quick and cost-effective routine application when run in a targeted fashion, but this method disregards events or circumstances not taken into account beforehand. We describe a method by one data set can serve for routine high throughput quantitative analysis and for versatile non-targeted investigations in a highly automated manner.
Contaminants of emerging concern (CEC) in the environment are generally described as compounds that are unknown or unrecognized, undetected or not routinely monitored, and represent a diverse group of chemicals that may pose a risk to human health and the environment. Due to limited analytical capability and available resources , monitoring of CECs has been focused on selected analytes rather than a holistic approach. We describe a new analytical method that can be used in the quantitative analysis of 61 targeted and 312 non-targeted CECs.
