This work uses IC with suppressed conductivity and mass spectrometry detection for organic acid determinations. This dual detection approach increases the information available from the sample. Samples were separated with a high-resolution Thermo Scientific™ Dionex™ IonPac™ AS11-HC-4μm column set using a Thermo Scientific™ Dionex™ Integrion™ HPIC™ system with suppressed conductivity detection, and an ISQ EC MS. Co-eluting organic acids can be accurately quantified with mass spectrometric detection, eliminating the need for the addition of methanol to the hydroxide eluent to enhance separation.
Organic acids and their salts such as citric acid, malic acid, formic acid, lactic acid, acetic acid, propionic acid, and fumaric acid are animal feed additives which play an important role in animal. In this application note, the animal feed sample is extracted with water. The extract is filtered or centrifuged and diluted, if necessary. The amounts and types of OAs from the sample are then determined using two IC methods. Method A is based on anion-exchange separation and method B is based on ion-exclusion separation. This is Method B. An ICS-6000 can be used for this application.
Organic acids and their salts such as citric acid, malic acid, formic acid, lactic acid, acetic acid, propionic acid, and fumaric acid are animal feed additives which play an important role in animal. In this application note, the animal feed sample is extracted with water. The extract is filtered or centrifuged and diluted, if necessary. The amounts and types of OAs from the sample are then determined using two IC methods. Method A is based on anion-exchange separation and method B is based on ion-exclusion separation. This is Method A. An ICS-6000 can be used for this application.
Ionic forms of air pollutants are analyzed here using anion-exchange chromatography and suppressed conductivity. The gas sample included particles < 2.5 um (PM2.5) was collected using ambient ion monitoring and then dissolved in deionized water. The dissolved inorganic anions and organic acids were separated on a 4 mm i.d. IonPac AS11-HC column and detected by suppressed conductivity. This method provided analysis of more ionic contaminants than standard methods (EPA Method 26A) and ASTM D5085-02). An ICS-6000 can be used for this application.
A direct injection method was designed using a Reagent‑Free™ Ion Chromatography (RFIC™) system with in-line sample cleanup to accurately and reproducibly measure oxalate in Bayer liquor. The online sample preparation removes most of the aluminum so that it does not contaminate either the column or suppressor. Fluoride is used to promote ligand exchange with oxalate for aluminum. This online sample preparation method allows an accurate, reproducible, and rugged determination of oxalate in Bayer liquor.
