Food safety and perceived health risks from residual agricultural chemicals are ongoing public concerns, and these chemicals are under increasing regulatory scrutiny, including polar pesticides. Much of the attention is focused on glyphosate because of its of wide use and association with crops and seeds genetically modified to tolerate glyphosate. In this application note, fast determination of multiple anionic pesticides and disinfection byproducts by IC-MS is demonstrated. All analytes of interest elute <14 min and were detected serially by suppressed conductivity and mass spectrometry.
A new workflow based on a modified QuPPe method and IC-MS/MS supports simultaneous multi-residue analysis of grape samples for polar pesticides. The IC-MS/MS method was developed using a Thermo Scientific™ Dionex™ IonPac™ AS19 4-µm column set and a compact IC system coupled to a Thermo Scientific™ TSQ Quantis™ triple quadrupole mass spectrometer. The results showed that the sensitivity, linearity,retention time precision, and recovery align with the SANTE/11813/2017 method performance criteria. The method provides lower LOQs than EU MRLs.
Food safety and perceived health risks from residual agricultural chemicals are ongoing public concerns, and these chemicals are under increasing regulatory scrutiny. The polar pesticides are one category, which include ionic post-emergent and desiccant herbicides, fungicides, growth-regulating chemicals, and the resultant metabolites of those compounds (Table 1 in the attached application note).
We demonstrated a simple workflow for the simultaneous analysis of melamine and analogues in pharmaceutical components using a Q Exactive benchtop Orbitrap mass spectrometer. The sensitive, simple and robust method employed the Thermo Fisher Scientific Q Exactive high resolution Orbitrap mass spectrometry coupled with UHPLC and HILIC mode chromatographic separation. Simultaneous detection and quantification of melamine and its analogues in Albumin and Guar gum were achieved with a high degree of confidence.
In March 2007, several North American manufacturers of pet food voluntarily issued nationwide recall notices for some of their products that were reportedly associated with renal failure in pets. It was discovered that melamine-contaminated China-sourced ingredients had been used to prepare feed for chickens, swine, and catfish. Consequently, the FDA and the USDA have developed methods for the analysis of melamine residues in animal tissue. Both methods use tandem MS detection and employ disposable strong cation exchange SPE cartridges to prepare samples for liquid chromatographic analysis.
