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AU205: Assay for Citrate and Phosphate in Pharmaceutical Formulations Using a High-Pressure Compact Ion Chromatography System
Description
Using ion chromatography methods to determine citrate and phosphate in pharmaceutical formulations has been previously demonstrated, validated, and adopted by The United States Pharmacopeia (USP) in General Chapter< 345>. The monograph specified an L61 column. Here we demonstrate that a higher porosity, higher capacity, and smaller particle size L81 column with similar selectivity to L61 has much higher efficiencies, capacities, and sensitivities, and extended linear range with reduced run times.| Market: | Pharma |
| Keywords: | Fast IC, Small particle column, Citrate, HPIC, RFIC, L61, phosphate, Integrion, Pharmaceutical Formulations, USP method, Microbore, <345>, IonPac AG11-HC-4µm, L81, AN164:AN 164, USP 345, USP General Chapter <345>, USP General Chapter 345 |
| Matrix: | Drug |
| Author: | Hua Yang, Linda Lopez, and Jeff Rohrer |
| Affiliation: | Thermo Fisher Scientific, Sunnyvale, CA USA |
For Research Use Only. Not for use in diagnostic procedures.
