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AU205: Assay for Citrate and Phosphate in Pharmaceutical Formulations Using a High-Pressure Compact Ion Chromatography System Be the first to rate this application

Description

Using ion chromatography methods to determine citrate and phosphate in pharmaceutical formulations has been previously demonstrated, validated, and adopted by The United States Pharmacopeia (USP) in General Chapter< 345>. The monograph specified an L61 column. Here we demonstrate that a higher porosity, higher capacity, and smaller particle size L81 column with similar selectivity to L61 has much higher efficiencies, capacities, and sensitivities, and extended linear range with reduced run times.
Market: Pharma
Keywords: Fast IC, Small particle column, Citrate, HPIC, RFIC, L61, phosphate, Integrion, Pharmaceutical Formulations, USP method, Microbore, IonPac AG11-HC-4µm, L81
Matrix: Drug
Author: Hua Yang, Linda Lopez, and Jeff Rohrer
Uploaded on 10/26/2016.

For Research Use Only. Not for use in diagnostic procedures.