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Separation of Oxidized and Deamidated Impurities from Denosumab by Reverse Phase Chromatography.
Description
The Thermo Scientific Dionex UltiMate 3000 LC Bio-LC system is applied for the Reverse phase analysis of Denosumab. The separation was performed on a Thermo Scientific MabPac RP column with a UV detection of 214 nm. With a run time of 80 minutes, the method allows easy separation of oxidized and Deamidated impurities.| Market: | BioPharma |
| Keywords: | HPLC, MAbPac RP, Denosumab, PDA detection, Oxidation, Deamidation |
| Matrix: | N/A |
| Author: | Manish Singh |
| Affiliation: | Thermo Fisher Scientific, APAC CoE Lab, Ahmedabad, India |
For Research Use Only. Not for use in diagnostic procedures.
