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Update of AN151: Determination of Perchlorate in High Salt Matrix Using a Compact Ion Chromatography System Coupled to a Mass Spectrometer Be the first to rate this application

Description

Perchlorate, an industrial contaminant from rockets, munitions, and fireworks, causes thyroid dysfunction in humans, especially pregnant women and children. In 2002, the EPA recommended a Provisional Reference Dose for perchlorate of 1 µg/L in drinking water. In 2015, California established a MCL of 6 µg/L with a Public Health Goal of 1 µg/L. IC-MS can provide lower detection limits (~ 30 ng/L) than conductivity in high-ionic-strength matrices using the MS selectivity at 99/101 m/z. Here we update Application Note AN151 with the Integrion IC system combined with the MSQ Plus mass spectrometer.
Market: Environmental
Keywords: MSQ Plus, Perchlorate, IonPac AS20 column, IC-MS, Integrion, Integrion HPIC, Integrion RFIC, LSSM, IC-ESI, IC-MS perchlorate, laboratory synthetic sample matrix, 99 m/z, 101 m/z, 107 m/z, high ionic matrix, para chlorobenzenesulfonic acid, parachlorobenzenesulfonic acid, 191 m/z, EPA 332.0, pCBSA
Matrix: 1000 mg/L LSSM laboratory synthetic matrix
Author: Yukiko Kawahara, Terri Christison, and Mike Hvizd
Affiliation: Thermo Fisher Scientific
Uploaded on 4/18/2016.

For Research Use Only. Not for use in diagnostic procedures.