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Determination of Galactosamine Containing Organic Impurities in Heparin Using a Compact Ion Chromatography System
Description
This record shows that AN233 can be run using an Integrion ion chromatography system. In AN233, the organic impurities in heparin are determined by HPAE-PAD using the Dionex CarboPac PA20 column following the USP monograph method. This method provides sensitive determination of galactosamine in acid-hydrolyzed heparin samples, enabling the identification of heparin that has been contaminated with chondroitin sulfates.Market: | BioPharma |
Keywords: | heparin, USP, ion chromatography, HPAE-PAD, CarboPac PA20 Column, Integrion, TN 20, TN 70671, TN70671, N20, AN233, TN176 |
Matrix: | Water |
Author: | Jingli Hu; Jeff Rohrer |
Affiliation: | Thermo Fisher Scientific, Sunnyvale, CA USA |
For Research Use Only. Not for use in diagnostic procedures.