The Thermo Scientific Dionex UltiMate 3000 LC system is applied for the analysis of ceftriaxone sodium and its impurities. The separation was performed on a Thermo Scientific Syncronis C18 HPLC column using the method described in the EP 8.0 monograph. The results obtained for resolution exceeded the criteria stated in the EP monograph. Resolution between ceftriaxone sodium and impurity A (ceftriaxone sodium E isomer) was 10.0 (EP criteria of minimum 3.0).

The Thermo Scientific Dionex UltiMate 3000 LC system is applied for the analysis of bimatoprost and its impurities. The separation was performed on a Thermo Scientific Accucore Phenyl-Hexyl HPLC column using a simple isocratic reversed-phase method.

The Thermo Scientific HPLC system is applied for the determination of oxymorphone and its isomer from human plasma. The samples are prepared using Thermo Scientific HyperSep solid supported liquid-liquid extraction (SLE), and the separation performed using a Thermo Scientific Hypersil GOLD HPLC column. For Research Use Only. Not for use in diagnostic procedures.

The Thermo Scientific HPLC system is applied for the analysis of lisinopril. The separation is performed on a Thermo Scientific Accucore RP-MS column, with UV detection at 210 nm.

In this work the Thermo Scientific Acclaim C30 column provides good resolution between both vitamin K1 and vitamin K2 and corresponding isomers, while the C18 column fails to separate these isomers.