We present an IC-MS/MS based method for high-throughput screening and quantitation of polar pesticide residues and their metabolites in water matrices below the current legislative requirements. Direct injection eliminates long and laborious sample preparation and makes the method more sensitive and faster than traditionally used LC-MS/MS methods, which utilize FMOC derivatization. This method can increase cost savings, provide more reliable results, and increase sample throughput.

The use of ASE in the extraction of chlorinated herbicides from solid wastes is more convenient, faster, and less solvent-intensive than previous methods.U.S. In the method reported in this application note, chlorinated herbicide recoveries by ASE are equivalent to recoveries from the wrist-shaking method recommended in Method 8150A. The procedures described in this application note meet the requirements for sample extraction as prescribed by U.S. EPA Method 3545.

Polychlorinated dibenzo-p-dioxins (PCDDs) and polychlorinated dibenzofurans (PCDFs) are toxic at low concentrations and therefore highly regulated. Additionally, these contaminants are difficult to extract. Accelerated Solvent Extraction (ASE) is an equivalent extraction method for U.S. EPA Methods 3545. ASE uses solvents at elevated temperatures and pressures, thereby increasing the extraction efficiency while consuming small amounts of solvent at significantly less time. Here ASE has been used to extract PCDDs and PCDFs from ground chimney brick, urban dust, fly ash, and sediment samples.

We present the reliable and accurate quantitative analysis of contaminants at the pg/mL level in drinking water using the Thermo Scientific EQuan MAX Plus LC-MS system coupled to the Thermo Scientific TSQ Endura triple quadrupole mass spectrometer. Excellent reproducibility was shown for the target compounds in tap water using 1 mL injections at 0.37× maximum effluent concentration.

Forensic toxicologists need an economical solution to screen for a virtually unlimited number of compounds in urine. Here we present a method for screening using a dilute-and-shoot approach with the Q Exactive Focus mass spectrometer and Thermo Scientific ToxFinder software. For forensic use only.