Five-fold increase in method throughput compared to original method (fifty samples/hour). Associated 10-fold reduction in cost per sample through reduced mobile phase consumption and waste generation. Additional reduced method complexity from easy-to-prepare mobile phase

The Thermo Scientific HPLC system is applied for the determination of fenoprofen. The separation was performed on a Thermo Scientific Accucore RP-MS column, with a run time of 7 minutes and UV detection at 272 nm. The method of analysis is based on the USP monograph, and was scaled down by using an in-house method transfer calculator.

The Thermo Scientific HPLC system is applied for the analysis of fenoprofen according to the USP monograph. The separation is performed on a Thermo Scientific Accucore XL C8 HPLC column, with UV detection at 272 nm.

The USP monograph for Fenoprofen, requires an L7 column with 5µm packing, therefore a Thermo Scientific Syncronis C8, 5µm column would be suitable and is demonstrated in this work.

The rapid determination of gemfibrozil was performed on a Thermo Scientific Accucore C18 HPLC column with MS detection. The analysis cycle time was 3.5 minutes.