Detection and Quantitation of Brominated and Chlorinated Hydrocarbons by DART with Linear Ion Trap and Triple Quadrupole Technology

Instrument Type: MSMS

Brominated hydrocarbons (BFRs) have been used in various industries for decades. Most chlorinated pesticides (OCs) have been banned in the United States, but their use still occurs in developing countries. The persistence of BFRs and OCs in the environment, potential deleterious activity, makes the detection and monitoring of these compounds an important topic. We propose DART as a simple, rapid, easy-to-use technique; eliminating the need for chromatographic method development, and reducing or eliminating sample preparation, for detection and quantitation of both BFRs and OCs.

Analyzing Residual Solvents in Pharmaceutical Products Using GC Headspace with Valve-and-Loop Sampling

Instrument Type: GC

This application note describes the analysis of residual solvents in accordance with USP method <467> using the Thermo Scientific™ TRACE™ 1310 GC, the new Thermo Scientific™ TriPlus™ 300 Headspace autosampler, and the Thermo Scientific™ Dionex™ Chromeleon™ chromatography data system (CDS) software. The method details the chromatographic system and analytical conditions to be used and addresses the acceptable limits for each solvent.

Consolidated GC-MS/MS Analysis of OCPs, PAHs, and PCBs in Environmental Samples

Instrument Type: GCMSMS

This application describes the analysis of semivolatile compounds like Organochlorine pesticides (OCP), polyaromatic hydrocarbons (PAH), and polychlorinated biphenyls (PCB) in various environmental matrices, showing the productivity and high quality results of a consolidated GC-MS/MS method using the Thermo Scientific™ TRACE™ 1310 GC and the TSQ™ 8000 triple quadrupole GC-MS/MS. It also describes the use of smart software tools that are integrated into the method development and analysis workflow to minimize the time needed to implement and maintain the methodology in routine.

Analysis of BTEX and Chlorinated Compounds in Water via a Dual Detector Configuration Gas Chromatograph

Instrument Type: GC

The application describes the determination of water pollutants as volatile aromatics and chlorinated hydrocarbons through a dual detector configuration of the Trace1310 GC, using the FID for the quantitation of the aromatic hydrocarbons and a more selective ECD for the quantitation of the halogenated compounds. A double detector configuration allows the simultaneous analysis of both classes of compounds, thanks to a post-column splitting of the effluents to the two detectors. A dedicated Dual Detector Kit has been used to guarantee inertness of the sample path and no dead volumes.