Acesulfame potassium, saccharin, aspartame, and sucralose are all commonly used artificial sweeteners that have been approved for use by the United States Food and Drug Administration (FDA). Sodium cyclamate has been banned in the United States, although it is approved for use in many other countries, including the UK. We demonstrate the use of the Thermo Scientific Accucore RP-MS HPLC column for the rapid analysis of five artificial sweeteners.

This work demonstrates the determination of the API (amphetamine) and counterions (aspartate, saccharin and sulfate) in a medicine Adderall within a single analysis using a Thermo Scientific Acclaim Trinity P2 column and Thermo Scientific Dionex Corona Veo Charged Aerosol Detector (CAD).

The Thermo Scientific Dionex UltiMate 3000 RS system is applied for the analysis of electrolytes in sports beverages. The separation is performed on a Thermo Scientific Acclaim Trinity P2 column, which is designed to resolve a broad range of anions and cations, mono- or multi-valent, in a single analysis using a simple gradient method. The Thermo Scientific OnGuard II P cartridge was used to remove artificial colors from the samples.

This application combines the Acclaim Trinity P1 with charged aerosol and diode array detection to quantify stevioside sweeteners used in foods and beverages. The two detectors are complimentary at higher concentrations of steviosides, but under the conditions used here the charged aerosol detector provides superior sensitivity for most of the analytes.

The Thermo Scientific UltiMate 3000 RSLC system is applied for the analysis of triclosan in toothpaste. The separation is performed on a Thermo Scientific Acclaim C8 RSLC column, with UV detection at 218 nm.