This work demonstrates the determination of the API (amphetamine) and counterions (aspartate, saccharin and sulfate) in a medicine Adderall within a single analysis using a Thermo Scientific Acclaim Trinity P2 column and Thermo Scientific Dionex Corona Veo Charged Aerosol Detector (CAD).

The Thermo Scientific Dionex UltiMate 3000 RS system is applied for the analysis of electrolytes in sports beverages. The separation is performed on a Thermo Scientific Acclaim Trinity P2 column, which is designed to resolve a broad range of anions and cations, mono- or multi-valent, in a single analysis using a simple gradient method. The Thermo Scientific OnGuard II P cartridge was used to remove artificial colors from the samples.

The Thermo Scientific Acclaim Trinity P2 used in HILIC mode separated malitol and isomalt in cough drops using a simple HILIC method.

The Thermo Scientific Acclaim Trinity P2 provides HILIC interactions in addition to anion-exchange and cation-exchange properties. It is shown here that both monosaccharides (fructose and glucose) and disaccharides (sucrose and lactose) can be sufficiently retained and separated on a 50 mm long column in 80% acetonitrile at 60 °C.

The Thermo Scientific Acclaim Trinity P2 column was used to determine a small amount of guanidine in a background of phosphate buffered saline (PBS). Even though the high concentration of sodium chloride overloads the column, it has sufficient resolution for quantifying all the components.