A new workflow based on a modified QuPPe method and IC-MS/MS supports simultaneous multi-residue analysis of grape samples for polar pesticides. The IC-MS/MS method was developed using a Thermo Scientific™ Dionex™ IonPac™ AS19 4-µm column set and a compact IC system coupled to a Thermo Scientific™ TSQ Quantis™ triple quadrupole mass spectrometer. The results showed that the sensitivity, linearity,retention time precision, and recovery align with the SANTE/11813/2017 method performance criteria. The method provides lower LOQs than EU MRLs.
Food safety and perceived health risks from residual agricultural chemicals are ongoing public concerns, and these chemicals are under increasing regulatory scrutiny. The polar pesticides are one category, which include ionic post-emergent and desiccant herbicides, fungicides, growth-regulating chemicals, and the resultant metabolites of those compounds (Table 1 in the attached application note).
We present a reliable and cost-effective IC-MS/MS multi-residue method for high-throughput screening and quantitation of polar pesticide residues and their metabolites in food matrices below the current legislative requirements. In contrast to methods described in the literature, sample preparation is simplified and the use of ion chromatography speeds up the separation.
We present a sensitive, robust, fast method to determine and quantify residues of polar pesticides in food samples in complex matrices at required regulatory levels. The Thermo Scientific UltiMate 3400 RSLC system is used in combination with a Thermo Scientific TSQ Quantiva triple quadrupole mass spectrometer to analyze QuPPe method extracts. The robustness of the system allows uninterrupted analysis of up to 500 honey samples and easy cleaning of the ion introduction system.
