We developed a sensitive and automated method using CIC to determine both TOF and EOF in FCM. The TOF method is beneficial for manufacturers to comply with current state regulations. We also employed a non-targeted LC-HRMS approach, which allowed us to detect 46 PFAS compounds in the EOF fraction, many of which fall outside of the typical list of targeted screening or quantification methods.
In AN003644, we developed a method to measure TOF in FCM using combustion-ion chromatography (C-IC). This application proof note demonstrates the determination of TOF in FCM using an enhanced C-IC system. The Thermo Scientific™ Cindion™ C-IC System combines the Thermo Scientific™ Dionex™ Inuvion™ IC System with the Thermo Scientific™ Cindion™ Combustion/Absorption Module, which minimizes PFAS contamination sources and includes a compact Z-fold combustion tube alongside full system control via Thermo Scientific™ Chromeleon™ Chromatography Data System (CDS) software.
Per- and polyfluoroalkyl substances (PFAS) is the collective name for over 14,000 synthetic fluorinated compounds. In addition to their extensive presence, PFAS compounds are persistent and bioaccumulate. Consequently, PFAS compounds are an environmental contamination concern. Toxicological studies of several PFAS compounds indicate the potential for acute to chronic effects impacting reproductive health. In this application, EPA Method 1621 is implemented on the Thermo Scientific Cindion C-IC designed for more efficient combustions and to minimize contamination sources.
Industries are adopting methods to enhance analytical performance while minimizing ecological impact. In ion chromatography, using microbore columns with diameters of 2 mm or less reduces eluent use, cutting hazardous waste and improving throughput.This note highlights rapid anion analysis in water using microbore column, which significantly reduces liquid waste compared to standard bore columns. This method enhances safety and sustainability by minimizing waste production.Both chemical and electrolytic suppression techniques are demonstrated.
An ion chromatography-mass spectrometry (IC-MS) method to meet the analytical need of understanding the sample composition and degradation byproduct in simulated battery electrolytes. Integrating an organic solvent gradient, this method achieves excellent separation of many analytes allowing lithium-ion battery (LIB) manufacturers and researchers to gain knoledge to improve quality assurance, quality control and failure analysis processes to ensure the battery's performance.
