A robust, sensitive, and reliable multi-residue LC-MS/MS method workflow solution that uses the Thermo Scientific TSQ Altis triple quadrupole mass spectrometer provides analysis and quantitation of more than 160 veterinary drugs with the Thermo Scientific VetDrugs Explorer Collection solution in salmon (fillet), bovine muscle, and milk. The complete instrument and data processing method including SRM settings is included with the VetDrugs Explorer Collection start-to-finish workflow solution. In 17 minutes, the target veterinary drugs were detected and quantified in food matrices.
The Thermo Scientific Dionex UltiMate 3000 LC system is applied for the related substances analysis for Cefazolin as per EP. The analysis was performed on a Thermo Scientific Hypersil Gold HPLC column using the method described in the EP 8.1 Monograph. The results obtained for resolution met the criteria as per EP. The results obtained for the resolution between Cefazolin & impurity L is found to be 5.3 (EP criteria is NLT 2.0).
The Thermo Scientific UltiMate 3000 HPLC system is applied for the determination of cephalosporins. The separation is performed on a Thermo Scientific Syncronis C18 HPLC column, with UV detection at 254 nm.
The Thermo Scientific HPLC system is applied for the analysis of antibiotics. The separation is performed on a Thermo Scientific Hypersil GOLD HPLC column, with UV detection at 254 nm.
The Thermo Scientific HPLC system is applied for the analysis of antibiotics in aqueous environmental matrices. The separation is performed on a Thermo Scientific Acclaim RSLC C18 column, with UV detection at 254 nm.
