The method transfer between the Thermo Scientific™ UltiMate™ 3000 UHPLC system and a Thermo Scientific™ Vanquish™ Flex UHPLC system is seamless and, in this case, for an isocratic separation requires no method redevelopment. The Thermo Scientific™ Acclaim™ Mixed Mode WAX-1 column proved capable of the analysis of neutral and ionic compounds that would be otherwise poorly retained on solely reversed-phase columns.The %RSD of peak area was found to be at least 50% lower for the majority of compounds analysed using the Thermo Scientific Vanquish Flex systems proprietary autosampler technology.
The analysis of food additives in carbonated beverages is important as many additives are controlled as part of the formulations of these beverages. In addition, analysis may detect possible counterfeiting of branded products. Being able to identify and quantify food additives in beverages quickly and with high sensitivity is therefore important.
Forensic toxicologists need an economical solution to screen for a virtually unlimited number of compounds in urine. Here we present a method for screening using a dilute-and-shoot approach with the Q Exactive Focus mass spectrometer and Thermo Scientific ToxFinder software. For forensic use only.
Contaminants of emerging concern (CEC) in the environment are generally described as compounds that are unknown or unrecognized, undetected or not routinely monitored, and represent a diverse group of chemicals that may pose a risk to human health and the environment. Due to limited analytical capability and available resources , monitoring of CECs has been focused on selected analytes rather than a holistic approach. We describe a new analytical method that can be used in the quantitative analysis of 61 targeted and 312 non-targeted CECs.
Pharmaceuticals and personal care products (PPCPs) and endocrine disrupting chemicals (EDCs) detected in surface and drinking waters, as well as in treated wastewater. They are an issue of increasing international attention due to potential environmental impacts. We developed an analytical method capable of determining PPCPs and their by-products in wastewater treatment plant (WWTP) samples. This workflow was applied in a survey of 35 permeate samples obtained from a pilot anaerobic membrane bioreactor (AnMBR).
