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Displaying 1-5 of 14 results

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Method validation based on ICH guidelines of an USP assay method of acetaminophen

Instrument Type: HPLC

Demonstrate the ease of implementation and processing of a full method validation that Chromeleon CDS performs with the eWorkflows based on the ICH guidelines.

Method transfer of a USP derived acetaminophen assay from an Agilent 1260 Infinity system to an UltiMate 3000 SD system and a Vanquish Flex UHPLC system

Instrument Type: HPLC

This application demonstrates the straightforward transfer of an analytical HPLC method from an Agilent 1260 Infinity instrument to a Thermo Scientific UltiMate 3000 HPLC system and a Thermo Scientific Vanquish Flex UHPLC system with the example of a USP derived assay for the analysis of acetaminophen and its impurities.

Method transfer of a USP-derived acetaminophen assay from an UltiMate 3000 SD system to a Vanquish Flex UHPLC system

Instrument Type: HPLC

This application demonstrates the straightforward transfer of an analytical HPLC method from a Thermo Scientific UltiMate 3000 HPLC system to a Thermo Scientific Vanquish Flex UHPLC system demonstrated with a USP derived assay for the analysis of acetaminophen and its impurities.

Simultaneous high-performance and ultra-highperformance liquid chromatographic analysis of acetaminophen impurities using a single instrument

Instrument Type: UHPLC

This application demonstrates the utilization of the Thermo Scientific Vanquish Flex Duo UHPLC system for Dual LC for the parallel implementation of independent HPLC and UHPLC methods at two independent flow paths in one instrument stack. For illustration the speed-up of a legacy HPLC method for acetaminophen impurity analysis to an optimized UHPLC method is described.

Forensic Screening for Drugs in Urine Using High-Resolution MS/MS Spectra and Simplified High-Performance Screening Software

Instrument Type: LCMSMS

Forensic toxicologists need an economical solution to screen for a virtually unlimited number of compounds in urine. Here we present a method for screening using a dilute-and-shoot approach with the Q Exactive Focus mass spectrometer and Thermo Scientific ToxFinder software. For forensic use only.