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Simultaneous high-performance and ultra-highperformance liquid chromatographic analysis of acetaminophen impurities using a single instrument
Description
This application demonstrates the utilization of the Thermo Scientific Vanquish Flex Duo UHPLC system for Dual LC for the parallel implementation of independent HPLC and UHPLC methods at two independent flow paths in one instrument stack. For illustration the speed-up of a legacy HPLC method for acetaminophen impurity analysis to an optimized UHPLC method is described.| Market: | Pharma |
| Keywords: | API, HPLC, UHPLC, Active pharmaceutical ingredient, Dual LC, speed-up |
| Matrix: | Methanol |
| Author: | Maria Grübner, Carsten Paul, Frank Steiner |
| Affiliation: | Thermo Fisher Scientific, Germering, Germany |
For Research Use Only. Not for use in diagnostic procedures.
