A streamlined TOF workflow using the Cindion C-IC system was developed for PFAS screening in cosmetic products. The method has a TF detection limit of approximately 0.91 ppm, well below the level of 100 ppm often used as a screening threshold for high-fluorine samples, and the method is highly accurate and precise for both TF and TIF determination.
This is additional data not reported in AN268. Shows the effect of a Dionex IonPac CTC-1 trap column trapping interfering dissolved iron from manually prepared MSA eluent. This trap can be used in other applications where acidic eluents might have dissolved metal contamination.
The Thermo Scientific™ Vanquish™ Horizon UHPLC coupled with the Thermo Scientific™ TSQ Quantis™ Plus mass spectrometer is used for the separation and detection of drugs of abuse in urine matrix. The SPE extraction uses Thermo Scientific™ SOLAμ™ SCX SPE plates for minimal sample and solvent volumes. Using a Thermo Scientific™ Accucore™ C18+ column with a total run time of 7 minutes, all isomers were separated including codeine / hydrocodone, and hydromorphone / morphine / norhydrocodone. The method includes 106 of the most tested drugs of abuse for easy adaption to customer labs.
The Thermo Scientific™ Vanquish™ Horizon UHPLC coupled with the Thermo Scientific™ Stellar™ mass spectrometer is used for the separation and detection of drugs of abuse in oral fluid matrix. The SPE extraction uses XTR tips with mixed mode SCX/WAX chemistry. Using a Thermo Scientific™ Accucore™ Biphenyl column with a total run time of 4.5 minutes, all isomers were separated, including methamphetamine / phentermine and hydromorphone / morphine. The method includes both CID (resonance-type, unique to ion traps) and HCD (beam-type) activations for more optimized fragmentation.
The Thermo Scientific™ Vanquish™ Horizon UHPLC coupled with the Thermo Scientific™ Orbitrap Exploris™ mass spectrometer is used for the separation and detection of drugs of abuse in urine matrix. The SPE extraction uses Thermo Scientific™ SOLAμ™ SCX SPE plates for minimal sample and solvent volumes. Using a Thermo Scientific™ Accucore™ C18+ column with a total run time of 7 minutes, all isomers were separated including codeine / hydrocodone, and hydromorphone / morphine / norhydrocodone. The method includes 106 of the most tested drugs of abuse for easy adaption to customer labs.
