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Case study: Instrument and LC column migration for the purification and analysis of synthetic oligonucleotides Be the first to rate this application

Description

Application note 003192 - A simple method to purify oligonucleotides via the Thermo Scientific™ Vanquish™ Analytical Purification LC System and to perform quality control using UHPLC-UV
Market: Pharma; Clinical Research
Keywords: oligonucleotides, Vanquish Flex Binary UHPLC system, fraction collection, Hypersil GOLD reversed phase column, purification, semi-preparative, Vanquish Fraction Collector, Chromeleon Chromatography Data System (CDS)
Matrix: 100mM TEAA
Author: Dennis Köhler
Affiliation: Thermo Fisher Scientific, CMD
Uploaded on 4/25/2025.