pH gradient with Vanquish Flex UHPLC system and MAbPAc SCX-10
DescriptionCharge variants analysis by ion exchange chromatography is one of the major analyses in biotherapeutics characterization. Here we show charge variant analysis of a therapeutic antibody with The Thermo Scientific Vanquish Flex UHPLC in combination with the Thermo Scientific MAbPac SCX-10, 5 µm. The ion exchange separation was performed in pH gradient mode by usingthe Thermo Scientific CX-1 pH-Gradient buffers.
|Keywords:||Monoclonal antibody, Proteins|
For Research Use Only. Not for use in diagnostic procedures.