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Improving sensitivity with SOLAμ for analytes susceptible to issues during pre-concentration dry down Be the first to rate this application

improving sensitivity with solaμ for analytes susceptible issues during preconcentration dry down

Description

The Thermo Scientific Dionex Ultimate 3000 system is applied to demonstrate the use of Thermo Scientific SOLAμ SPE product for the extraction of analytes such as Ibuprofen which are susceptible to loss or degradation during evaporation and reconstitution. The use of a Thermo Scientific Accucore HPLC column provided fast and efficient separation without the need for an ultra high pressure system. MS/MS detection was performed on a Thermo Scientific TSQ Vantage mass spectrometer. For Research Use Only. Not for use in diagnostic procedures.
Market: Pharma
Keywords: matrix effects, micro elution, No dry down, reproducibility, SOLAμ, SPE
Matrix: Rat plasma
Uploaded on 10/17/2014.

For Research Use Only. Not for use in diagnostic procedures.