SOLAμ for pre-analysis sample concentration to improve sensitivity

Instrument Type: LCMS

This work demonstrates the use of Thermo Scientific SOLAμ SPE product to enhance sample pre-concentration prior to analysis. Additional benefits include reduced workflow and improved stability for analytes susceptible to loss or degradation during evaporation and reconstitution. The use of a Thermo Scientific Accucore HPLC column provided fast and efficient separation without the need for an ultra high pressure system. MS/MS detection was performed on a Thermo Scientific TSQ Vantage mass spectrometer. For Research Use Only. Not for use in diagnostic procedures.

The application of SOLAμ for reduced sample volume analysis demonstrated with Niflumic acid.

Instrument Type: LCMS

The Thermo Scientific Dionex Ultimate 3000 system is applied to demonstrate how the Thermo Scientific SOLAμ SPE product can be used to facilitate the scale down of an extraction method when sample volume is limited. The Thermo Scientific Accucore HPLC column provided fast and efficient separation without the need for an ultra high pressure system. MS/MS detection was performed on a Thermo Scientific TSQ Vantage mass spectrometer. For Research Use Only. Not for use in diagnostic procedures.

Improving sensitivity with SOLAμ for analytes susceptible to issues during pre-concentration dry down

Instrument Type: HPLC

The Thermo Scientific Dionex Ultimate 3000 system is applied to demonstrate the use of Thermo Scientific SOLAμ SPE product for the extraction of analytes such as Ibuprofen which are susceptible to loss or degradation during evaporation and reconstitution. The use of a Thermo Scientific Accucore HPLC column provided fast and efficient separation without the need for an ultra high pressure system. MS/MS detection was performed on a Thermo Scientific TSQ Vantage mass spectrometer. For Research Use Only. Not for use in diagnostic procedures.