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Displaying 1-3 of 3 results for Tag: muscle relaxant

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Separation of related impurities of Methocarbamol Injection.

Instrument Type: HPLC

The Thermo Scientific Dionex UltiMate 3000 LC system is applied for the separation of related impurities of Methocarbamol Injection. The separation was performed on a Thermo Scientific Acclaim Phenyl-1 HPLC column with UV detection at 276 nm. With a total run time of 65 minutes the method allows separation of all related impurities of Methocarbamol.

Separation of Related Impurities from Vercuronium Bromide as per BP monograph.

Instrument Type: HPLC

The Thermo Scientific Dionex UltiMate 3000 LC system is applied for the analysis of Vercuronium Bromide. The separation was performed on a Thermo Scientific Acclaim Polar Advantage-II HPLC column using the method described in BP monograph. The results obtained for Resolution exceeded the criteria stated in the BP. Resolution between Vercuronium Bromide and Impurity-C was 8.97 ( met BP criteria of NLT 1.2), Resolution between Vercuronium Bromide and Impurity-F was 2.15 (met BP criteria of NLT 1.2) and Resolution between Vercuronium Bromide and Impurity-B was 10.78 (met BP criteria NLT 2.0).

Improved analysis of choline, acetylcholine, and succinylcholine using a Thermo Scientific Acclaim Trinity P1 column with charged aerosol detection

Instrument Type: HPLC-CAD

The Thermo Scientific Dionex Ultimate 3000 RSLC system with quaternary LPG is applied for the analysis of anesthetic and muscle relaxants. The separation was performed in less than 12 minutes on a Thermo Scientific Dionex Acclaim Trinity P1 3 µm column with a Thermo Scientific Dionex Corona Ultra charged aerosol detector (CAD).